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Last Published 05.01.2026 Effective Date: 05.01.2026 This policy addresses the use of Ketalar (ketamine) for anesthesia purposes and Spravato (esketamine) for the treatment of treatment-resistant depression (TRD) and major depressive disorder (MDD)

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Risk assessment and mitigation strategies should be discussed

These investigations continue to contribute valuable knowledge regarding peptide-mediated biological communication systems